A heavier ready rig on a 3/0 circle — bull reds, keeper grouper and big whole baits.
Fluorocarbon is what makes it a Ghost rig. It refracts light close to the way water does, so it is far harder to see than mono, and it takes abrasion when a big fish runs you into reef or piling.
Circle hook technique applies as always: no hookset, let the rod load, wind steadily.